Kernels 2.6.16 and newer provide a mechanism to have the kernel drop the page cache and/or inode and dentry caches on command, which can help free up a lot of memory. Now you can throw away that script that allocated a ton of memory just to get rid of the cache...

To use /proc/sys/vm/drop_caches, just echo a number to it.

To free pagecache:

# echo 1 > /proc/sys/vm/drop_caches

To free dentries and inodes:

# echo 2 > /proc/sys/vm/drop_caches

To free pagecache, dentries and inodes:

echo 3 > /proc/sys/vm/drop_caches

As this is a non-destructive operation and dirty objects are not freeable, the user should run "sync" first!